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Two-stage analyses of sequence variants in association with quantitative traits

We propose a two-stage design for the analysis of sequence variants in which a proportion of genes that show some evidence of association are identified initially and then followed up in an independent data set. We compare two different approaches. In both approaches the same summary measure (total...

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Detalles Bibliográficos
Autores principales: Barrett, Jennifer H, Nsengimana, Jérémie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3287891/
https://www.ncbi.nlm.nih.gov/pubmed/22373079
http://dx.doi.org/10.1186/1753-6561-5-S9-S53