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Gene-based Higher Criticism methods for large-scale exonic single-nucleotide polymorphism data
In genome-wide association studies, gene-based methods measure potential joint genetic effects of loci within genes and are promising for detecting causative genetic variations. Following recent theoretical research in statistical multiple-hypothesis testing, we propose to adapt the Higher Criticism...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2011
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3287904/ https://www.ncbi.nlm.nih.gov/pubmed/22373436 http://dx.doi.org/10.1186/1753-6561-5-S9-S65 |