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Principal components ancestry adjustment for Genetic Analysis Workshop 17 data

Statistical tests on rare variant data may well have type I error rates that differ from their nominal levels. Here, we use the Genetic Analysis Workshop 17 data to estimate type I error rates and powers of three models for identifying rare variants associated with a phenotype: (1) by using the numb...

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Detalles Bibliográficos
Autores principales: Jin, Jing, Cerise, Jane E, Kang, Sun Jung, Yoon, Eun Jung, Yoon, Seungtai, Mendell, Nancy R, Finch, Stephen J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3287905/
https://www.ncbi.nlm.nih.gov/pubmed/22373457
http://dx.doi.org/10.1186/1753-6561-5-S9-S66