Identifying variants that contribute to linkage for dichotomous and quantitative traits in extended pedigrees

Compared to genome-wide association analysis, linkage analysis is less influenced by allelic heterogeneity. The use of linkage information in large families should provide a great opportunity to identify less frequent variants. We perform a linkage scan for both dichotomous and quantitative traits i...

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Detalles Bibliográficos
Autores principales: Chen, Wei-Min, Manichaikul, Ani, Rich, Stephen S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Proceedings
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3287907/
https://www.ncbi.nlm.nih.gov/pubmed/22373516
http://dx.doi.org/10.1186/1753-6561-5-S9-S68

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3287907/
https://www.ncbi.nlm.nih.gov/pubmed/22373516
http://dx.doi.org/10.1186/1753-6561-5-S9-S68

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