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Integrating binary traits with quantitative phenotypes for association mapping of multivariate phenotypes
Clinical binary end-point traits are often governed by quantitative precursors. Hence it may be a prudent strategy to analyze a clinical end-point trait by considering a multivariate phenotype vector, possibly including both quantitative and qualitative phenotypes. A major statistical challenge lies...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3287913/ https://www.ncbi.nlm.nih.gov/pubmed/22373144 http://dx.doi.org/10.1186/1753-6561-5-S9-S73 |