Cargando…
Identity-by-descent filtering as a tool for the identification of disease alleles in exome sequence data from distant relatives
Large-scale, deep resequencing may be the next logical step in the genetic investigation of common complex diseases. Because each individual is likely to carry many thousands of variants, the identification of causal alleles requires an efficient strategy to reduce the number of candidate variants....
| Autores principales: | , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2011
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3287916/ https://www.ncbi.nlm.nih.gov/pubmed/22373213 http://dx.doi.org/10.1186/1753-6561-5-S9-S76 |