Strategies for selection of subjects for sequencing after detection of a linkage peak

Linkage analysis has the potential to localize disease genes of interest, but the choice of which subjects to select for follow-up sequencing after identifying a linkage peak might influence the ability to find a disease gene. We compare nine different strategies for selection of subjects for follow...

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Detalles Bibliográficos
Autores principales: Allen-Brady, Kristina, Farnham, James, Cannon-Albright, Lisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Proceedings
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3287917/
https://www.ncbi.nlm.nih.gov/pubmed/22373232
http://dx.doi.org/10.1186/1753-6561-5-S9-S77

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3287917/
https://www.ncbi.nlm.nih.gov/pubmed/22373232
http://dx.doi.org/10.1186/1753-6561-5-S9-S77

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