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Using linkage analysis of large pedigrees to guide association analyses

To date, genome-wide association studies have yielded discoveries of common variants that partly explain familial aggregation of diseases and traits. Researchers are now turning their attention to less common variants because the price of sequencing has dropped drastically. However, because sequenci...

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Detalles Bibliográficos
Autores principales: Choi, Seung-Hoan, Liu, Chunyu, Dupuis, Josée, Logue, Mark W, Jun, Gyungah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3287919/
https://www.ncbi.nlm.nih.gov/pubmed/22373287
http://dx.doi.org/10.1186/1753-6561-5-S9-S79