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A novel method to detect rare variants using both family and unrelated case-control data
To detect rare variants associated with a phenotype, we develop a novel statistical method that can use both family and unrelated case-control data. Unlike the currently existing methods, we first use family data to calculate weights to be given to rare variants, differentiating between concordantly...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2011
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3287921/ https://www.ncbi.nlm.nih.gov/pubmed/22373319 http://dx.doi.org/10.1186/1753-6561-5-S9-S80 |