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A method to detect single-nucleotide polymorphisms accounting for a linkage signal using covariate-based affected relative pair linkage analysis

We evaluate an approach to detect single-nucleotide polymorphisms (SNPs) that account for a linkage signal with covariate-based affected relative pair linkage analysis in a conditional-logistic model framework using all 200 replicates of the Genetic Analysis Workshop 17 family data set. We begin by...

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Detalles Bibliográficos
Autores principales: Song, Yeunjoo E, Namkung, Junghyun, Shields, Robert W, Baechle, Daniel J, Song, Sunah, Elston, Robert C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3287925/
https://www.ncbi.nlm.nih.gov/pubmed/22373405
http://dx.doi.org/10.1186/1753-6561-5-S9-S84