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A pathway-based association analysis model using common and rare variants

How various genetic effects in combination affect susceptibility to certain disease states continues to be a major area of methodological research. Various rare variant models have been proposed, in response to a common failure to either identify or validate biologically driven causal genetic varian...

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Detalles Bibliográficos
Autores principales: Cheng, Lu, Hu, Pingzhao, Sykes, Jenna, Pintilie, Melania, Liu, Geoffrey, Xu, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3287926/
https://www.ncbi.nlm.nih.gov/pubmed/22373433
http://dx.doi.org/10.1186/1753-6561-5-S9-S85