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Evaluation of association tests for rare variants using simulated data sets in the Genetic Analysis Workshop 17 data

We evaluate four association tests for rare variants—the combined multivariate and collapsing (CMC) method, two weighted-sum methods, and a variable threshold method—by applying them to the simulated data sets of unrelated individuals in the Genetic Analysis Workshop 17 (GAW17) data. The family-wise...

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Detalles Bibliográficos
Autores principales: Chen, Wenan, Gao, Xi, Wang, Jiexun, Sun, Chuanyu, Wan, Wen, Zhi, Degui, Liu, Nianjun, Chen, Xiangning, Gao, Guimin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3287927/
https://www.ncbi.nlm.nih.gov/pubmed/22373475
http://dx.doi.org/10.1186/1753-6561-5-S9-S86