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Evaluation of association tests for rare variants using simulated data sets in the Genetic Analysis Workshop 17 data
We evaluate four association tests for rare variants—the combined multivariate and collapsing (CMC) method, two weighted-sum methods, and a variable threshold method—by applying them to the simulated data sets of unrelated individuals in the Genetic Analysis Workshop 17 (GAW17) data. The family-wise...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3287927/ https://www.ncbi.nlm.nih.gov/pubmed/22373475 http://dx.doi.org/10.1186/1753-6561-5-S9-S86 |