Do rare variant genotypes predict common variant genotypes?

The synthetic association hypothesis proposes that common genetic variants detectable in genome-wide association studies may reflect the net phenotypic effect of multiple rare polymorphisms distributed broadly within the focal gene rather than, as often assumed, the effect of common functional varia...

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Detalles Bibliográficos
Autores principales: Kent, Jack W, Farook, Vidya, Göring, Harald HH, Dyer, Thomas D, Almasy, Laura, Duggirala, Ravindranath, Blangero, John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Proceedings
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3287928/
https://www.ncbi.nlm.nih.gov/pubmed/22373504
http://dx.doi.org/10.1186/1753-6561-5-S9-S87

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3287928/
https://www.ncbi.nlm.nih.gov/pubmed/22373504
http://dx.doi.org/10.1186/1753-6561-5-S9-S87

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