Cargando…
Association tests for rare and common variants based on genotypic and phenotypic measures of similarity between individuals
Genome-wide association studies have helped us identify thousands of common variants associated with several widespread complex diseases. However, for most traits, these variants account for only a small fraction of phenotypic variance or heritability. Next-generation sequencing technologies are bei...
Autores principales: | , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3287930/ https://www.ncbi.nlm.nih.gov/pubmed/22373048 http://dx.doi.org/10.1186/1753-6561-5-S9-S89 |