Cargando…
Association tests for rare and common variants based on genotypic and phenotypic measures of similarity between individuals
Genome-wide association studies have helped us identify thousands of common variants associated with several widespread complex diseases. However, for most traits, these variants account for only a small fraction of phenotypic variance or heritability. Next-generation sequencing technologies are bei...
Autores principales: | Thalamuthu, Anbupalam, Zhao, Jingyuan, Keong, Garrett Teoh Hor, Kondragunta, Venkateswarlu, Mukhopadhyay, Indranil |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3287930/ https://www.ncbi.nlm.nih.gov/pubmed/22373048 http://dx.doi.org/10.1186/1753-6561-5-S9-S89 |
Ejemplares similares
-
A comparison between microsatellite and single-nucleotide polymorphism markers with respect to two measures of information content
por: Thalamuthu, Anbupalam, et al.
Publicado: (2005) -
Gene-based multiple trait analysis for exome sequencing data
por: Zhao, Jingyuan, et al.
Publicado: (2011) -
Do rare variant genotypes predict common variant genotypes?
por: Kent, Jack W, et al.
Publicado: (2011) -
Identity by descent and association analysis of dichotomous traits based on large pedigrees
por: Liu, Tian, et al.
Publicado: (2011) -
Comparison of similarity-based tests and pooling strategies for rare variants
por: Zakharov, Sergii, et al.
Publicado: (2013)