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Addition of multiple rare SNPs to known common variants improves the association between disease and gene in the Genetic Analysis Workshop 17 data

The upcoming release of new whole-genome genotyping technologies will shed new light on whether there is an associative effect of previously immeasurable rare variants on incidence of disease. For Genetic Analysis Workshop 17, our team focused on a statistical method to detect associations between g...

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Detalles Bibliográficos
Autores principales: Sykes, Jenna, Cheng, Lu, Xu, Wei, Tsao, Ming-Sound, Liu, Geoffrey, Pintilie, Melania
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3287939/
https://www.ncbi.nlm.nih.gov/pubmed/22373301
http://dx.doi.org/10.1186/1753-6561-5-S9-S97