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Identifying rare variants using a Bayesian regression approach

Recent advances in next-generation sequencing technologies have made it possible to generate large amounts of sequence data with rare variants in a cost-effective way. Statistical methods that test variants individually are underpowered to detect rare variants, so it is desirable to perform associat...

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Detalles Bibliográficos
Autores principales: Yan, Aimin, Laird, Nan M, Li, Cheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3287941/
https://www.ncbi.nlm.nih.gov/pubmed/22373362
http://dx.doi.org/10.1186/1753-6561-5-S9-S99