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Mechanism-Based Screen Establishes Signalling Framework for DNA Damage-Associated G1 Checkpoint Response
DNA damage activates checkpoint controls which block progression of cells through the division cycle. Several different checkpoints exist that control transit at different positions in the cell cycle. A role for checkpoint activation in providing resistance of cells to genotoxic anticancer therapy,...
Autores principales: | Richardson, Elizabeth, Stockwell, Simon R., Li, He, Aherne, Wynne, Cuomo, Maria Emanuela, Mittnacht, Sibylle |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3288045/ https://www.ncbi.nlm.nih.gov/pubmed/22384045 http://dx.doi.org/10.1371/journal.pone.0031627 |
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