Non-Small Cell Lung Carcinoma Cell Motility, Rac Activation and Metastatic Dissemination Are Mediated by Protein Kinase C Epsilon

BACKGROUND: Protein kinase C (PKC) ε, a key signaling transducer implicated in mitogenesis, survival, and cancer progression, is overexpressed in human primary non-small cell lung cancer (NSCLC). The role of PKCε in lung cancer metastasis has not yet been established. PRINCIPAL FINDINGS: Here we sho...

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Detalles Bibliográficos
Autores principales: Caino, M. Cecilia, Lopez-Haber, Cynthia, Kissil, Joseph L., Kazanietz, Marcelo G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3288050/
https://www.ncbi.nlm.nih.gov/pubmed/22384062
http://dx.doi.org/10.1371/journal.pone.0031714

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3288050/
https://www.ncbi.nlm.nih.gov/pubmed/22384062
http://dx.doi.org/10.1371/journal.pone.0031714

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