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Intracellular Alkalinization Induces Cytosolic Ca(2+) Increases by Inhibiting Sarco/Endoplasmic Reticulum Ca(2+)-ATPase (SERCA)
Intracellular pH (pHi) and Ca(2+) regulate essentially all aspects of cellular activities. Their inter-relationship has not been mechanistically explored. In this study, we used bases and acetic acid to manipulate the pHi. We found that transient pHi rise induced by both organic and inorganic bases,...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3288054/ https://www.ncbi.nlm.nih.gov/pubmed/22384096 http://dx.doi.org/10.1371/journal.pone.0031905 |