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Intracellular Alkalinization Induces Cytosolic Ca(2+) Increases by Inhibiting Sarco/Endoplasmic Reticulum Ca(2+)-ATPase (SERCA)

Intracellular pH (pHi) and Ca(2+) regulate essentially all aspects of cellular activities. Their inter-relationship has not been mechanistically explored. In this study, we used bases and acetic acid to manipulate the pHi. We found that transient pHi rise induced by both organic and inorganic bases,...

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Detalles Bibliográficos
Autores principales: Li, Sen, Hao, Baixia, Lu, Yingying, Yu, Peilin, Lee, Hon-Cheung, Yue, Jianbo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3288054/
https://www.ncbi.nlm.nih.gov/pubmed/22384096
http://dx.doi.org/10.1371/journal.pone.0031905

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