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The Extended Cleavage Specificity of Human Thrombin

Thrombin is one of the most extensively studied of all proteases. Its central role in the coagulation cascade as well as several other areas has been thoroughly documented. Despite this, its consensus cleavage site has never been determined in detail. Here we have determined its extended substrate r...

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Detalles Bibliográficos
Autores principales: Gallwitz, Maike, Enoksson, Mattias, Thorpe, Michael, Hellman, Lars
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3288055/
https://www.ncbi.nlm.nih.gov/pubmed/22384068
http://dx.doi.org/10.1371/journal.pone.0031756