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A Crosstalk between the Smad and JNK Signaling in the TGF-β-Induced Epithelial-Mesenchymal Transition in Rat Peritoneal Mesothelial Cells

Transforming growth factor β (TGF-β) induces the process of epithelial-mesenchymal transition (EMT) through the Smad and JNK signaling. However, it is unclear how these pathways interact in the TGF-β1-induced EMT in rat peritoneal mesothelial cells (RPMCs). Here, we show that inhibition of JNK activ...

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Detalles Bibliográficos
Autores principales: Liu, Qinghua, Zhang, Yu, Mao, Haiping, Chen, Wei, Luo, Ning, Zhou, Qin, Chen, Wenfang, Yu, Xueqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3288060/
https://www.ncbi.nlm.nih.gov/pubmed/22384127
http://dx.doi.org/10.1371/journal.pone.0032009