Cargando…

A Crosstalk between the Smad and JNK Signaling in the TGF-β-Induced Epithelial-Mesenchymal Transition in Rat Peritoneal Mesothelial Cells

Transforming growth factor β (TGF-β) induces the process of epithelial-mesenchymal transition (EMT) through the Smad and JNK signaling. However, it is unclear how these pathways interact in the TGF-β1-induced EMT in rat peritoneal mesothelial cells (RPMCs). Here, we show that inhibition of JNK activ...

Descripción completa

Detalles Bibliográficos
Autores principales:	Liu, Qinghua, Zhang, Yu, Mao, Haiping, Chen, Wei, Luo, Ning, Zhou, Qin, Chen, Wenfang, Yu, Xueqing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3288060/ https://www.ncbi.nlm.nih.gov/pubmed/22384127 http://dx.doi.org/10.1371/journal.pone.0032009

Ejemplares similares

Acetylation of HMGB1 by JNK1 Signaling Promotes LPS-Induced Peritoneal Mesothelial Cells Apoptosis
por: Cao, Shirong, et al.
Publicado: (2018)

Elabela Attenuates the TGF-β1-Induced Epithelial-Mesenchymal Transition of Peritoneal Mesothelial Cells in Patients Receiving Peritoneal Dialysis
por: Xie, Shunyun, et al.
Publicado: (2022)

The Effect of Statin on Epithelial-Mesenchymal Transition in Peritoneal Mesothelial Cells
por: Chang, Tae Ik, et al.
Publicado: (2014)

Effects of tranilast on the epithelial-to-mesenchymal transition in peritoneal mesothelial cells
por: Kang, Seok Hui, et al.
Publicado: (2019)

Effect of aldosterone on epithelial-to-mesenchymal transition of human peritoneal mesothelial cells
por: Yu, Mina, et al.
Publicado: (2015)

Mechanisms of Epithelial-Mesenchymal Transition of Peritoneal Mesothelial Cells During Peritoneal Dialysis
por: Lee, Hi Bahl, et al.
Publicado: (2007)

Effects of TGF-β1 Receptor Inhibitor GW788388 on the Epithelial to Mesenchymal Transition of Peritoneal Mesothelial Cells
por: Lho, Yunmee, et al.
Publicado: (2021)

Hydrogen sulfide inhibits epithelial-mesenchymal transition in peritoneal mesothelial cells
por: Cheng, Shengnan, et al.
Publicado: (2018)

Shorter daily dwelling time in peritoneal dialysis attenuates the epithelial-to-mesenchymal transition of mesothelial cells
por: Lee, Yi-Che, et al.
Publicado: (2014)

Blocking Posttranslational Core Fucosylation Ameliorates Rat Peritoneal Mesothelial Cell Epithelial-Mesenchymal Transition
por: Li, Long-Kai, et al.
Publicado: (2017)

TGF-β1 induces peritoneal fibrosis by activating the Smad2 pathway in mesothelial cells and promotes peritoneal carcinomatosis
por: Lv, Zhi-Dong, et al.
Publicado: (2023)

miRNA589 Regulates Epithelial-Mesenchymal Transition in Human Peritoneal Mesothelial Cells
por: Zhang, Ke, et al.
Publicado: (2012)

Suppression of Hepatic Epithelial-to-Mesenchymal Transition by Melittin via Blocking of TGFβ/Smad and MAPK-JNK Signaling Pathways
por: Park, Ji-Hyun, et al.
Publicado: (2017)

TGF-β1 Receptor Inhibitor SB525334 Attenuates the Epithelial to Mesenchymal Transition of Peritoneal Mesothelial Cells via the TGF-β1 Signaling Pathway
por: Heo, Jung-Yoon, et al.
Publicado: (2021)

Fibrin-Induced Epithelial-to-Mesenchymal Transition of Peritoneal Mesothelial Cells as a Mechanism of Peritoneal Fibrosis: Effects of Pentoxifylline
por: Fang, Cheng-Chung, et al.
Publicado: (2012)

Histone deacetylase 6 inhibition counteracts the epithelial–mesenchymal transition of peritoneal mesothelial cells and prevents peritoneal fibrosis
por: Xu, Liuqing, et al.
Publicado: (2017)

Mesothelial-to-Mesenchymal Transition and Exosomes in Peritoneal Metastasis of Ovarian Cancer
por: Pascual-Antón, Lucía, et al.
Publicado: (2021)

Effect of TGF-β(1) Stimulation on the Smad Signal Transduction Pathway of Human Peritoneal Mesothelial Cells
por: Zhang, Hao, et al.
Publicado: (2005)

Reprogramming of Mesothelial-Mesenchymal Transition in Chronic Peritoneal Diseases by Estrogen Receptor Modulation and TGF-β1 Inhibition
por: Wilson, Robert B., et al.
Publicado: (2020)

Trehalose ameliorates peritoneal fibrosis by promoting Snail degradation and inhibiting mesothelial-to-mesenchymal transition in mesothelial cells
por: Miyake, Taito, et al.
Publicado: (2020)

Epithelial to Mesenchymal Transition of Mesothelial Cells in Tuberculous Pleurisy
por: Kim, Changhwan, et al.
Publicado: (2011)

Nintedanib attenuates peritoneal fibrosis by inhibiting mesothelial‐to‐mesenchymal transition, inflammation and angiogenesis
por: Liu, Feng, et al.
Publicado: (2021)

Tamoxifen Ameliorates Peritoneal Membrane Damage by Blocking Mesothelial to Mesenchymal Transition in Peritoneal Dialysis
por: Loureiro, Jesús, et al.
Publicado: (2013)

Matrine suppresses lipopolysaccharide-induced fibrosis in human peritoneal mesothelial cells by inhibiting the epithelial-mesenchymal transition
por: Li, Yi-Zheng, et al.
Publicado: (2019)

MiR-29b may suppresses peritoneal metastases through inhibition of the mesothelial–mesenchymal transition (MMT) of human peritoneal mesothelial cells
por: Kimura, Yuki, et al.
Publicado: (2022)

Are the Mesothelial-to-Mesenchymal Transition, Sclerotic Peritonitis Syndromes, and Encapsulating Peritoneal Sclerosis Part of the Same Process?
por: Loureiro, Jesús, et al.
Publicado: (2013)

Requirement of Histone Deacetylase 6 for Interleukin-6 Induced Epithelial-Mesenchymal Transition, Proliferation, and Migration of Peritoneal Mesothelial Cells
por: Shi, Yingfeng, et al.
Publicado: (2021)

MiR-30b is involved in methylglyoxal-induced epithelial-mesenchymal transition of peritoneal mesothelial cells in rats
por: Liu, Hong, et al.
Publicado: (2014)

S100A4 amplifies TGF-β-induced epithelial–mesenchymal transition in a pleural mesothelial cell line
por: Ning, Qian, et al.
Publicado: (2018)

Asiaticoside inhibits TGF-β1-induced mesothelial-mesenchymal transition and oxidative stress via the Nrf2/HO-1 signaling pathway in the human peritoneal mesothelial cell line HMrSV5
por: Zhao, Junyi, et al.
Publicado: (2020)

Genomic reprograming analysis of the Mesothelial to Mesenchymal Transition identifies biomarkers in peritoneal dialysis patients
por: Ruiz-Carpio, Vicente, et al.
Publicado: (2017)

Mesothelial‐to‐mesenchymal transition as a possible therapeutic target in peritoneal metastasis of ovarian cancer
por: Rynne‐Vidal, Angela, et al.
Publicado: (2017)

Vitamin D Can Ameliorate Chlorhexidine Gluconate-Induced Peritoneal Fibrosis and Functional Deterioration through the Inhibition of Epithelial-to-Mesenchymal Transition of Mesothelial Cells
por: Lee, Yi-Che, et al.
Publicado: (2015)

RhoA/Rho-kinase triggers epithelial-mesenchymal transition in mesothelial cells and contributes to the pathogenesis of dialysis-related peritoneal fibrosis
por: Wang, Qinglian, et al.
Publicado: (2018)

Serum Response Factor Accelerates the High Glucose-Induced Epithelial-to-Mesenchymal Transition (EMT) via Snail Signaling in Human Peritoneal Mesothelial Cells
por: He, Lijie, et al.
Publicado: (2014)

Thalidomide Inhibits TGF-β1-induced Epithelial to Mesenchymal Transition in Alveolar Epithelial Cells via Smad-Dependent and Smad-Independent Signaling Pathways
por: Zhou, Xian-Long, et al.
Publicado: (2017)

Activation of General Control Nonderepressible-2 Kinase Ameliorates Glucotoxicity in Human Peritoneal Mesothelial Cells, Preserves Their Integrity, and Prevents Mesothelial to Mesenchymal Transition
por: Eleftheriadis, Theodoros, et al.
Publicado: (2019)

The Crosstalk between Nrf2 and TGF-β1 in the Epithelial-Mesenchymal Transition of Pancreatic Duct Epithelial Cells
por: Arfmann-Knübel, Sarah, et al.
Publicado: (2015)

miR-200c Prevents TGF-β1-Induced Epithelial-to-Mesenchymal Transition and Fibrogenesis in Mesothelial Cells by Targeting ZEB2 and Notch1
por: Chu, Jessica Y.S., et al.
Publicado: (2019)

Repression of Smad4 by MicroRNA-1285 moderates TGF-β-induced epithelial–mesenchymal transition in proliferative vitreoretinopathy
por: Pao, Shu-I, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_bqfj2fght1rdrd1vjrqdj4qu1a