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NYESO-1/LAGE-1s and PRAME Are Targets for Antigen Specific T Cells in Chondrosarcoma following Treatment with 5-Aza-2-Deoxycitabine

BACKGROUND: Chondrosarcoma has no proven systemic option in the metastatic setting. The development of a non-cross-resistant strategy, such as cellular immunotherapy using antigen-specific T cells would be highly desirable. NY-ESO-1 and PRAME are members of the Cancer Testis Antigen (CTA) family tha...

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Detalles Bibliográficos
Autores principales: Pollack, Seth M., Li, Yonqing, Blaisdell, Megan J., Farrar, Erik A., Chou, Jeffrey, Hoch, Benjamin L., Loggers, Elizabeth T., Rodler, Eve, Eary, Janet F., Conrad, Ernest U., Jones, Robin L., Yee, Cassian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3288075/
https://www.ncbi.nlm.nih.gov/pubmed/22384167
http://dx.doi.org/10.1371/journal.pone.0032165