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Combined Chromatin and Expression Analysis Reveals Specific Regulatory Mechanisms within Cytokine Genes in the Macrophage Early Immune Response

Macrophages play a critical role in innate immunity, and the expression of early response genes orchestrate much of the initial response of the immune system. Macrophages undergo extensive transcriptional reprogramming in response to inflammatory stimuli such as Lipopolysaccharide (LPS). To identify...

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Detalles Bibliográficos
Autores principales: Jesus Iglesias, Maria, Reilly, Sarah-Jayne, Emanuelsson, Olof, Sennblad, Bengt, Pirmoradian Najafabadi, Mohammad, Folkersen, Lasse, Mälarstig, Anders, Lagergren, Jens, Eriksson, Per, Hamsten, Anders, Odeberg, Jacob
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3288078/
https://www.ncbi.nlm.nih.gov/pubmed/22384210
http://dx.doi.org/10.1371/journal.pone.0032306