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Combined Chromatin and Expression Analysis Reveals Specific Regulatory Mechanisms within Cytokine Genes in the Macrophage Early Immune Response
Macrophages play a critical role in innate immunity, and the expression of early response genes orchestrate much of the initial response of the immune system. Macrophages undergo extensive transcriptional reprogramming in response to inflammatory stimuli such as Lipopolysaccharide (LPS). To identify...
Autores principales: | Jesus Iglesias, Maria, Reilly, Sarah-Jayne, Emanuelsson, Olof, Sennblad, Bengt, Pirmoradian Najafabadi, Mohammad, Folkersen, Lasse, Mälarstig, Anders, Lagergren, Jens, Eriksson, Per, Hamsten, Anders, Odeberg, Jacob |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3288078/ https://www.ncbi.nlm.nih.gov/pubmed/22384210 http://dx.doi.org/10.1371/journal.pone.0032306 |
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