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[(11)C]flumazenil Binding Is Increased in a Dose-Dependent Manner with Tiagabine-Induced Elevations in GABA Levels

Evidence indicates that synchronization of cortical activity at gamma-band frequencies, mediated through GABA-A receptors, is important for perceptual/cognitive processes. To study GABA signaling in vivo, we recently used a novel positron emission tomography (PET) paradigm measuring the change in bi...

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Detalles Bibliográficos
Autores principales: Frankle, W. Gordon, Cho, Raymond Y., Mason, N. Scott, Chen, Chi-Min, Himes, Michael, Walker, Christopher, Lewis, David A., Mathis, Chester A., Narendran, Rajesh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3288104/
https://www.ncbi.nlm.nih.gov/pubmed/22384252
http://dx.doi.org/10.1371/journal.pone.0032443