γ-Aminobutyric Acid Transporter 2 Mediates the Hepatic Uptake of Guanidinoacetate, the Creatine Biosynthetic Precursor, in Rats

Guanidinoacetic acid (GAA) is the biosynthetic precursor of creatine which is involved in storage and transmission of phosphate-bound energy. Hepatocytes readily convert GAA to creatine, raising the possibility that the active uptake of GAA by hepatocytes is a regulatory factor. The purpose of this...

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Detalles Bibliográficos
Autores principales: Tachikawa, Masanori, Ikeda, Saori, Fujinawa, Jun, Hirose, Shirou, Akanuma, Shin-ichi, Hosoya, Ken-ichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3288109/
https://www.ncbi.nlm.nih.gov/pubmed/22384273
http://dx.doi.org/10.1371/journal.pone.0032557

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3288109/
https://www.ncbi.nlm.nih.gov/pubmed/22384273
http://dx.doi.org/10.1371/journal.pone.0032557

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