Cargando…
γ-Aminobutyric Acid Transporter 2 Mediates the Hepatic Uptake of Guanidinoacetate, the Creatine Biosynthetic Precursor, in Rats
Guanidinoacetic acid (GAA) is the biosynthetic precursor of creatine which is involved in storage and transmission of phosphate-bound energy. Hepatocytes readily convert GAA to creatine, raising the possibility that the active uptake of GAA by hepatocytes is a regulatory factor. The purpose of this...
Autores principales: | Tachikawa, Masanori, Ikeda, Saori, Fujinawa, Jun, Hirose, Shirou, Akanuma, Shin-ichi, Hosoya, Ken-ichi |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3288109/ https://www.ncbi.nlm.nih.gov/pubmed/22384273 http://dx.doi.org/10.1371/journal.pone.0032557 |
Ejemplares similares
-
Processing mechanism of guanidinoacetate in choroid plexus epithelial cells: conversion of guanidinoacetate to creatine via guanidinoacetate N-methyltransferase and monocarboxylate transporter 12-mediated creatine release into the CSF
por: Jomura, Ryuta, et al.
Publicado: (2022) -
Localization of organic anion transporting polypeptide (Oatp) 1a4 and Oatp1c1 at the rat blood-retinal barrier
por: Akanuma, Shin-ichi, et al.
Publicado: (2013) -
Lack of Epileptogenic Effects of the Creatine Precursor Guanidinoacetic Acid on Neuronal Cultures In Vitro
por: Poggio, Fabio, et al.
Publicado: (2022) -
Creatine, guanidinoacetate and homoarginine in statin-induced myopathy
por: Neu, Axel, et al.
Publicado: (2020) -
Effects of dietary guanidinoacetic acid on growth performance, guanidinoacetic acid absorption and creatine metabolism of lambs
por: Zhang, Shiqi, et al.
Publicado: (2022)