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Motion and Flexibility in Human Cytochrome P450 Aromatase
The crystal structures of human placental aromatase in complex with the substrate androstenedione and exemestane have revealed an androgen-specific active site and the structural basis for higher order organization. However, X-ray structures do not provide accounts of movements due to short-range fl...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2012
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3288111/ https://www.ncbi.nlm.nih.gov/pubmed/22384274 http://dx.doi.org/10.1371/journal.pone.0032565 |