Recombinant human DNase I decreases biofilm and increases antimicrobial susceptibility in staphylococci

Extracellular DNA is an adhesive component of staphylococcal biofilms. The aim of this study was to evaluate the antibiofilm activity of recombinant human DNase I (rhDNase) against Staphylococcus aureus and Staphylococcus epidermidis. Using a 96-well microtiter plate crystal violet binding assay, we...

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Detalles Bibliográficos
Autores principales: Kaplan, Jeffrey B., LoVetri, Karen, Cardona, Silvia T., Madhyastha, Srinivasa, Sadovskaya, Irina, Jabbouri, Saïd, Izano, Era A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3288126/
https://www.ncbi.nlm.nih.gov/pubmed/22167157
http://dx.doi.org/10.1038/ja.2011.113

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3288126/
https://www.ncbi.nlm.nih.gov/pubmed/22167157
http://dx.doi.org/10.1038/ja.2011.113

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