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Occludin is required for apoptosis when claudin–claudin interactions are disrupted
Disruption of tight junctions is often seen during pathogen infection, inflammation, and tumor progression. Mislocalization of the tight junction proteins occludin and claudin in mammary epithelial monolayers leads to apoptosis through the extrinsic pathway. To further investigate the mechanism of t...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2012
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3288343/ https://www.ncbi.nlm.nih.gov/pubmed/22361748 http://dx.doi.org/10.1038/cddis.2012.14 |