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Occludin is required for apoptosis when claudin–claudin interactions are disrupted

Disruption of tight junctions is often seen during pathogen infection, inflammation, and tumor progression. Mislocalization of the tight junction proteins occludin and claudin in mammary epithelial monolayers leads to apoptosis through the extrinsic pathway. To further investigate the mechanism of t...

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Detalles Bibliográficos
Autores principales: Beeman, N, Webb, P G, Baumgartner, H K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3288343/
https://www.ncbi.nlm.nih.gov/pubmed/22361748
http://dx.doi.org/10.1038/cddis.2012.14

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