Cargando…
Polyinosinic acid decreases sequestration and improves systemic therapy of measles virus
Off target binding or vector sequestration can significantly limit the efficiency of systemic virotherapy. We report here that systemically administered oncolytic measles virus (MV) was rapidly sequestered by the mononuclear phagocytic system (MPS) of the liver and spleen in measles receptor CD46-po...
| Autores principales: | , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2011
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3288770/ https://www.ncbi.nlm.nih.gov/pubmed/22116376 http://dx.doi.org/10.1038/cgt.2011.82 |