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Effect of Inducers, Incubation Time and Heme Concentration on IC(50) Value Variation in Anti-heme Crystallization Assay

Heme detoxification through crystallization into hemozoin has been suggested as a good target for the development of screening assays for new antimalarials. However, comparisons among the data obtained from different experiments are difficult, and the IC(50) values (the concentrations of drug that a...

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Detalles Bibliográficos
Autores principales: Nhien, Nguyen Thanh Thuy, Huy, Nguyen Tien, Uyen, Dinh Thanh, Deharo, Eric, Hoa, Pham Thi Le, Hirayama, Kenji, Harada, Shigeharu, Kamei, Kaeko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Tropical Medicine 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3289280/
https://www.ncbi.nlm.nih.gov/pubmed/22438701
http://dx.doi.org/10.2149/tmh.2011-29