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Effect of Inducers, Incubation Time and Heme Concentration on IC(50) Value Variation in Anti-heme Crystallization Assay
Heme detoxification through crystallization into hemozoin has been suggested as a good target for the development of screening assays for new antimalarials. However, comparisons among the data obtained from different experiments are difficult, and the IC(50) values (the concentrations of drug that a...
Autores principales: | Nhien, Nguyen Thanh Thuy, Huy, Nguyen Tien, Uyen, Dinh Thanh, Deharo, Eric, Hoa, Pham Thi Le, Hirayama, Kenji, Harada, Shigeharu, Kamei, Kaeko |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Japanese Society of Tropical Medicine
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3289280/ https://www.ncbi.nlm.nih.gov/pubmed/22438701 http://dx.doi.org/10.2149/tmh.2011-29 |
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