Regulation of Sirtuin Function by Posttranslational Modifications

Sirtuins are homologs of the yeast silencing information regulator 2 protein, an NAD(+)-dependent (histone) deacetylase. In mammals seven different sirtuins, SIRT1–7, have been identified, which share a common catalytic core domain but possess distinct N- and C-terminal extensions. This core domain...

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Detalles Bibliográficos
Autores principales: Flick, Franziska, Lüscher, Bernhard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Research Foundation 2012
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3289391/
https://www.ncbi.nlm.nih.gov/pubmed/22403547
http://dx.doi.org/10.3389/fphar.2012.00029

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3289391/
https://www.ncbi.nlm.nih.gov/pubmed/22403547
http://dx.doi.org/10.3389/fphar.2012.00029

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