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Sub-Lethal Irradiation of Human Colorectal Tumor Cells Imparts Enhanced and Sustained Susceptibility to Multiple Death Receptor Signaling Pathways

BACKGROUND: Death receptors (DR) of the TNF family function as anti-tumor immune effector molecules. Tumor cells, however, often exhibit DR-signaling resistance. Previous studies indicate that radiation can modify gene expression within tumor cells and increase tumor cell sensitivity to immune attac...

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Detalles Bibliográficos
Autores principales: Ifeadi, Victoria, Garnett-Benson, Charlie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3289623/
https://www.ncbi.nlm.nih.gov/pubmed/22389673
http://dx.doi.org/10.1371/journal.pone.0031762