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Structural Analysis of the C-Terminal Region (Modules 18–20) of Complement Regulator Factor H (FH)

Factor H (FH) is a soluble regulator of the human complement system affording protection to host tissues. It selectively inhibits amplification of C3b, the activation-specific fragment of the abundant complement component C3, in fluid phase and on self-surfaces and accelerates the decay of the alter...

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Detalles Bibliográficos
Autores principales: Morgan, Hugh P., Mertens, Haydyn D. T., Guariento, Mara, Schmidt, Christoph Q., Soares, Dinesh C., Svergun, Dmitri I., Herbert, Andrew P., Barlow, Paul N., Hannan, Jonathan P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3289644/
https://www.ncbi.nlm.nih.gov/pubmed/22389686
http://dx.doi.org/10.1371/journal.pone.0032187