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Structural Analysis of the C-Terminal Region (Modules 18–20) of Complement Regulator Factor H (FH)
Factor H (FH) is a soluble regulator of the human complement system affording protection to host tissues. It selectively inhibits amplification of C3b, the activation-specific fragment of the abundant complement component C3, in fluid phase and on self-surfaces and accelerates the decay of the alter...
Autores principales: | Morgan, Hugh P., Mertens, Haydyn D. T., Guariento, Mara, Schmidt, Christoph Q., Soares, Dinesh C., Svergun, Dmitri I., Herbert, Andrew P., Barlow, Paul N., Hannan, Jonathan P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3289644/ https://www.ncbi.nlm.nih.gov/pubmed/22389686 http://dx.doi.org/10.1371/journal.pone.0032187 |
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