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A Large Population Histology Study Showing the Lack of Association between ALT Elevation and Significant Fibrosis in Chronic Hepatitis B

OBJECTIVE: We determined the association between various clinical parameters and significant liver injury in both hepatitis B e antigen (HBeAg)-positive and HBeAg-negative patients. METHODS: From 1994 to 2008, liver biopsy was performed on 319 treatment-naïve CHB patients. Histologic assessment was...

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Detalles Bibliográficos
Autores principales: Seto, Wai-Kay, Lai, Ching-Lung, Ip, Philip P. C., Fung, James, Wong, Danny Ka-Ho, Yuen, John Chi-Hang, Hung, Ivan Fan-Ngai, Yuen, Man-Fung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3289659/
https://www.ncbi.nlm.nih.gov/pubmed/22389715
http://dx.doi.org/10.1371/journal.pone.0032622