Frequent Heterogeneous Missense Mutations of GGAP2 in Prostate Cancer: Implications for Tumor Biology, Clonality and Mutation Analysis

Prostate cancer is the most common visceral malignancy in Western men and a major cause of cancer deaths. Increased activation of the AKT and NFkB pathways have been identified as critical steps in prostate cancer initiation and progression. GGAP2 (GTP-binding and GTPase activating protein 2) is a m...

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Detalles Bibliográficos
Autores principales: Cai, Yi, Wang, Jianghua, Ren, Chengxi, Ittmann, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3289671/
https://www.ncbi.nlm.nih.gov/pubmed/22389719
http://dx.doi.org/10.1371/journal.pone.0032708

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3289671/
https://www.ncbi.nlm.nih.gov/pubmed/22389719
http://dx.doi.org/10.1371/journal.pone.0032708

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