Secretion and N-Linked Glycosylation Are Required for Prostatic Acid Phosphatase Catalytic and Antinociceptive Activity

Secretory human prostatic acid phosphatase (hPAP) is glycosylated at three asparagine residues (N62, N188, N301) and has potent antinociceptive effects when administered to mice. Currently, it is unknown if these N-linked residues are required for hPAP protein stability and activity in vitro or in a...

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Detalles Bibliográficos
Autores principales: Hurt, Julie K., Fitzpatrick, Brendan J., Norris-Drouin, Jacqueline, Zylka, Mark J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3289678/
https://www.ncbi.nlm.nih.gov/pubmed/22389722
http://dx.doi.org/10.1371/journal.pone.0032741

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3289678/
https://www.ncbi.nlm.nih.gov/pubmed/22389722
http://dx.doi.org/10.1371/journal.pone.0032741

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