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Molecular mechanisms controlling CFTR gene expression in the airway

The low levels of CFTR gene expression and paucity of CFTR protein in human airway epithelial cells are not easily reconciled with the pivotal role of the lung in cystic fibrosis pathology. Previous data suggested that the regulatory mechanisms controlling CFTR gene expression might be different in...

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Detalles Bibliográficos
Autores principales: Zhang, Zhaolin, Ott, Christopher J, Lewandowska, Marzena A, Leir, Shih-Hsing, Harris, Ann
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3289769/
https://www.ncbi.nlm.nih.gov/pubmed/21895967
http://dx.doi.org/10.1111/j.1582-4934.2011.01439.x