The PPAR Gamma Agonist Troglitazone Regulates Erk 1/2 Phosphorylation via a PPARγ-Independent, MEK-Dependent Pathway in Human Prostate Cancer Cells

Thiazolidinediones (TZDs) dramatically reduce the growth of human prostate cancer cells in vitro and in vivo. To determine whether the antitumor effects of TZDs were due in part to changes in the MEK/Erk signaling pathway, we examined the regulation of Erk phosphorylation by the TZD troglitazone wit...

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Detalles Bibliográficos
Autores principales: Bolden, Adrienne, Bernard, Lynikka, Jones, Danielle, Akinyeke, Tunde, Stewart, LaMonica V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3289875/
https://www.ncbi.nlm.nih.gov/pubmed/22448169
http://dx.doi.org/10.1155/2012/929052

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3289875/
https://www.ncbi.nlm.nih.gov/pubmed/22448169
http://dx.doi.org/10.1155/2012/929052

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