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Sensing prokaryotic mRNA signifies microbial viability and promotes immunity

Live vaccines have long been known to trigger far more vigorous immune responses than their killed counterparts(1–6). This has been attributed to the ability of live microorganisms to replicate and express specialized virulence factors that facilitate invasion and infection of their hosts(7). Howeve...

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Detalles Bibliográficos
Autores principales: Sander, Leif E., Davis, Michael J., Boekschoten, Mark V., Amsen, Derk, Dascher, Christopher C., Ryffel, Bernard, Swanson, Joel A., Müller, Michael, Blander, J. Magarian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3289942/
https://www.ncbi.nlm.nih.gov/pubmed/21602824
http://dx.doi.org/10.1038/nature10072