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Minocycline and aspirin in the treatment of bipolar depression: a protocol for a proof-of-concept, randomised, double-blind, placebo-controlled, 2×2 clinical trial

INTRODUCTION: New medication classes are needed to improve treatment effectiveness in the depressed phase of bipolar disorder (BD). Extant evidence suggests that BD is characterised by neural changes such as dendritic remodelling and glial and neuronal cell loss. These changes have been hypothesised...

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Detalles Bibliográficos
Autores principales: Savitz, Jonathan, Preskorn, Sheldon, Teague, T Kent, Drevets, Douglas, Yates, William, Drevets, Wayne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Group 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3289990/
https://www.ncbi.nlm.nih.gov/pubmed/22357572
http://dx.doi.org/10.1136/bmjopen-2011-000643