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Identification of TPIT and other novel autoantigens in lymphocytic hypophysitis; immunoscreening of a pituitary cDNA library and development of immunoprecipitation assays

BACKGROUND: Lymphocytic hypophysitis is an organ-specific autoimmune disease of the pituitary gland. A specific and sensitive serological test currently does not exist to aid in the diagnosis. OBJECTIVE: To identify target autoantigens in lymphocytic hypophysitis and develop a diagnostic assay for t...

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Detalles Bibliográficos
Autores principales: Smith, Casey Jo Anne, Bensing, Sophie, Burns, Christine, Robinson, Phillip J, Kasperlik-Zaluska, Anna A, Scott, Rodney J, Kämpe, Olle, Crock, Patricia A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioScientifica 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3290121/
https://www.ncbi.nlm.nih.gov/pubmed/22193973
http://dx.doi.org/10.1530/EJE-11-1015