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Probabilistic Inference for Nucleosome Positioning with MNase-Based or Sonicated Short-Read Data
We describe a model-based method, PING, for predicting nucleosome positions in MNase-Seq and MNase- or sonicated-ChIP-Seq data. PING compares favorably to NPS and TemplateFilter in scalability, accuracy and robustness to low read density. To demonstrate that PING predictions from widely available so...
Autores principales: | Zhang, Xuekui, Robertson, Gordon, Woo, Sangsoon, Hoffman, Brad G., Gottardo, Raphael |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3290535/ https://www.ncbi.nlm.nih.gov/pubmed/22393380 http://dx.doi.org/10.1371/journal.pone.0032095 |
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